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Integrative snRNA-seq and snATAC-seq profiling revealed the dynamic nuclear heterogeneity and lineage-specific regulatory architecture of the human placental syncytiotrophoblast

2022-08-08

Abstract excerpt

<title>Abstract</title> <p>The significance of the placenta in success pregnancy outcome has been generally acknowledged. Despite our growing understanding of placenta cellular compositions and function, the heterogeneity among billions of nuclei within the syncytiotrophoblast (STB), a multinucleated entity primarily responsible for placental function, remains largely understudied. To better understand the identi...

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Literature Corpus work
b2481f70-876c-59e0-afca-1add29585f5b
DOI
10.21203/rs.3.rs-1898137/v1
Open publication

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Integrative snRNA-seq and snATAC-seq profiling revealed the dynamic nuclear heterogeneity and lineage-specific regulatory architecture of the human placental syncytiotrophoblastDOI 10.21203/rs.3.rs-1898137/v1
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