Article

Comparative analysis of the syncytiotrophoblast in placenta tissue and trophoblast organoids using snRNA sequencing

2024-07-04

Abstract excerpt

The outer surface of chorionic villi in the human placenta consists of a single multinucleated cell called the syncytiotrophoblast (STB). The unique cellular ultrastructure of the STB presents challenges in deciphering its gene expression signature at the single-cell level, as the STB contains billions of nuclei in a single cell. There are many gaps in understanding the molecular mechanisms and developmental traje...

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Literature Corpus work: b5329039-6f5e-54e6-aca7-9dcc5674e1d2
DOI: 10.1101/2024.07.01.601571

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