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A single-cell survey of the human first-trimester placenta and decidua

5 Oct 2018

Abstract excerpt

The placenta and decidua interact dynamically to enable embryonic and fetal development. Here, we report single-cell RNA sequencing of 14,341 and 6754 cells from first-trimester human placental villous and decidual tissues, respectively. Bioinformatic analysis identified major cell types, many known and some subtypes previously unknown in placental villi and decidual context. Further detailed analysis revealed...

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PMID: 30402542
DOI: 10.1126/sciadv.aau4788

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