Article

Mendelian randomizations with spatial gene networks reveal shared and distinct drivers of risk in major skin cancer types

2025-03-01

Abstract excerpt

Skin cancer is the most common malignancy worldwide, comprising three major types: melanoma, basal cell carcinoma (BCC), and squamous cell carcinoma (SCC). A critical goal in advancing our understanding of skin cancer is to identify the shared and distinct biological mechanisms that drive the risk profiles for each skin cancer type. In this study, we integrated tissue-specific chromatin conformation and expression...

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Literature Corpus work: 16e11cc0-87d6-5c0d-b8f1-9e7f8a085c97
DOI: 10.1101/2025.02.25.640031

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