Article

Targeting of Th17-related cytokines in patients with Darier Disease

2023-01-17

Abstract excerpt

Darier disease (DD) is a rare, inherited multi-organ disorder associated with mutations in the ATP2A2 gene. DD patients often have skin involvement characterized by malodorous, inflamed skin and recurrent, severe infections. Therapeutic options are limited and inadequate for the long-term management of this chronic disease. Using gene and protein expression profiling assays, we demonstrate enhanced expression of T...

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Literature Corpus work: b1fbb525-f752-5377-b666-10d4272d38a6
DOI: 10.1101/2023.01.12.22283857

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