Article

Dopamine and risky decision-making in pathological and problem gamblers

2019-10-16

Abstract excerpt

Gambling disorder is a behavioral addiction that is associated with impairments in value-based decision-making such as increased temporal discounting and reduced risk-aversion. Dopamine regulates learning and decision-making by modulating information processing throughout fronto-striatal circuits. Although the role of alterations in dopamine neurotransmission in the etiology of gambling disorder is controversial,...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: b1864353-856c-5594-b58a-0d4f9473a106
DOI: 10.1101/805929

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Dopamine and risky decision-making in pathological and problem gamblersDOI 10.1101/805929Read

The drift diffusion model as the choice rule in inter-temporal and risky choice: a case study in medial orbitofrontal cortex lesion patients and controlsSemantic proximity Read

Cortical dopamine reduces the impact of motivational biases governing automated behaviourSemantic proximity Read

COMT Val158Met Genotype Determines the Direction of Cognitive Effects Produced by Catechol-O-Methyltransferase InhibitionSemantic proximity Read

Computational phenotyping of brain-behavior dynamics underlying approach-avoidance conflict in major depressive disorder.Semantic proximity Read

Replication study implicates COMT val158met polymorphism as a modulator of probabilistic reward learning.Semantic proximity Read

D2 dopamine receptor expression, sensitivity to rewards, and reinforcement learning in a complex value-based decision-making taskSemantic proximity Read

A proof of concept study of tolcapone for pathological gambling: relationships with COMT genotype and brain activation.Semantic proximity Read

Risk and Loss Aversion and Attitude to COVID and Vaccines in Anxious IndividualsSemantic proximity Read

Untenable Dynamics of Reward Sensitivity in Adolescents with Major Depressive DisorderSemantic proximity Read

Impulsivity in rodents with a genetic predisposition for excessive alcohol consumption is associated with a lack of a prospective strategy.Semantic proximity Read

Dissociable contribution of prefrontal and striatal dopaminergic genes to learning in economic games.Semantic proximity Read

Individual differences in learning and decision-making: the role of COMT Val158Met polymorphism in transitive inference.Semantic proximity Read