Article

Non-invasive imaging of estrogen receptor-coregulator interaction by luciferase fragment complementation

2012-01-01

Abstract excerpt

Breast cancer is the most common cancer in the UK and approximately 1 in 8 women will be affected by the disease. Estrogen regulates breast cancer growth through the action of the estrogen receptors ERα and ERβ. Antiestrogens, in particular tamoxifen, have contributed greatly to the reduction in breast cancer mortality. Tamoxifen is a tissue selective antiestrogen; it is antiestrogenic in the breast but estrogenic...

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Literature Corpus work: b18020b0-789f-553d-9205-7f4f840aa9fd
DOI: 10.25560/9256

Open publication

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