Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

IFN-γ 874A>T genotype is associated with higher CCR5 expression in peripheral blood mononuclear cells from HIV+ patients.

Journal of acquired immune deficiency syndromes (1999) - 15 Dec 2011

Liptrott Neill J, Egan Deirdre, Back David J, Owen Andrew

Abstract excerpt

We previously showed that certain cytokines impact on the expression of drug transporters and chemokine receptors in peripheral blood mononuclear cells. Known single-nucleotide polymorphism genes in the genes encoding interferon γ (874A>T, rs62559044) and interleukin 2 (-330T>G, rs2069763) were genotyped in 66 HIV+ patients, and the impact of single-nucleotide polymorphisms on expression of ABCB1, ABCC1, ABCC2,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Alleles
Share to Gene Expression Regulation
Share to HIV Infections
Share to Interferon-gamma
Share to Leukocytes, Mononuclear
Share to Multidrug Resistance-Associated Protein 2
Share to Polymorphism, Single Nucleotide
Share to Receptors, CCR5

Source

Identifiers

PMID: 21926633
DOI: 10.1097/QAI.0b013e318236441c

Genes

CCR5
ABCB1
ABCC1
ABCC2
CXCR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

IFN-γ 874A>T genotype is associated with higher CCR5 expression in peripheral blood mononuclear cells from HIV+ patients.PMID 21926633Read ↗

Targeted next-generation sequencing approach for CCR5, CXCR4 and IFNAR1 genes in HIV+ participants: Association of single nucleotide polymorphisms with CD4+ T cell count and HIV replication in patients receiving antiretroviral therapySemantic proximity Read ↗

Polymorphisms of CCR5, IL-6, IFN-γ and IL-10 genes in Cuban HIV/AIDS patients.Semantic proximity Read ↗

A FcɣRIIa polymorphism has a HLA-B57 and HLA-B27 independent effect on HIV disease outcome.Semantic proximity Read ↗

The impact of the role of cytokines on HIV infection in people living with HIV with and without comorbidities.Semantic proximity Read ↗

IFN-stimulated gene expression is independent of the IFNL4 genotype in chronic HIV-1 infection.Semantic proximity Read ↗

Interferon lambda rs368234815 ΔG/ΔG is associated with higher CD4+:CD8+ T-cell ratio in treated HIV-1 infection.Semantic proximity Read ↗

Methamphetamine Facilitates HIV Infection of Human Monocytes Through Inhibiting Cellular Viral Restriction FactorsSemantic proximity Read ↗

IFNL4 rs368234815 polymorphism is associated with innate resistance to HIV-1 infection.Semantic proximity Read ↗

RXRγ gene variants are associated with HIV lipodystrophy.Semantic proximity Read ↗

ABCB1 4036A>G and 1236C>T Polymorphisms Affect Plasma Efavirenz Levels in South African HIV/AIDS PatientsSemantic proximity Read ↗

CC chemokine receptor 5 cell-surface expression in relation to CC chemokine receptor 5 genotype and the clinical course of HIV-1 infection.Semantic proximity Read ↗

Relationship between polymerase gamma (POLG) polymorphisms and antiretroviral therapy-induced lipodystrophy in HIV-1 infected patients: a case-control study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.