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Evolutionary unique <i>N</i> -glycan-dependent protein quality control system plays pivotal roles in cellular fitness and extracellular vesicle transport in <i>Cryptococcus neoformans</i>

2024-09-25

Abstract excerpt

A conserved N -glycan-dependent endoplasmic reticulum protein quality control (ERQC) system has evolved in eukaryotes to ensure accuracy during glycoprotein folding. The human pathogen Cryptococcus neoformans possesses a unique N -glycosylation pathway that affects microbial physiology and interactions with the infected host. To investigate the molecular features and functions of the ERQC system in C. neoforma...

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Literature Corpus work
b136c17d-c5cc-5365-9a16-7e77635d49dc
DOI
10.1101/2024.09.24.610715
Open publication

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