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Article

Unraveling unique structure and biosynthesis pathway of N-linked glycans in human fungal pathogen Cryptococcus neoformans by glycomics analysis.

The Journal of biological chemistry - 1 Jun 2012

Park Jeong-Nam, Lee Dong-Jik, Kwon Ohsuk, Oh Doo-Byoung, Bahn Yong-Sun, Kang Hyun Ah

Abstract excerpt

The encapsulated fungal pathogen Cryptococcus neoformans causes cryptococcosis in immunocompromised individuals. Although cell surface mannoproteins have been implicated in C. neoformans pathogenicity, the structure of N-linked glycans assembled on mannoproteins has not yet been elucidated. By analyzing oligosaccharide profiles combined with exoglycosidase treatment, we report here that C. neoformans has...

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Identifiers

PMID: 22500028
DOI: 10.1074/jbc.M112.354209
PMCID: PMC3365987

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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