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Mice Overexpressing Wild Type RRAS2: A Novel Preclinical Model for Testing Anti-Chronic Lymphocytic Leukemia Therapies

2023-09-21

Abstract excerpt

B-cell chronic lymphocytic leukemia (B-CLL) is the most common type of leukemia in the Western world. Mutations in different genes, such as TP53 and ATM, and deletions in specific chromosomal regions, including 11q or 17p, have been associated with a worse prognosis for the disease. Recent research from our group has demonstrated that, contrary to the usual cancer development process through missense mutations, B-...

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Literature Corpus work
b12d9c45-4583-584a-ae79-aa5ecb44157b
DOI
10.20944/preprints202309.1417.v1
Open publication

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Mice Overexpressing Wild Type RRAS2: A Novel Preclinical Model for Testing Anti-Chronic Lymphocytic Leukemia TherapiesDOI 10.20944/preprints202309.1417.v1
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