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Article

Evidence of latent-lytic replication in EBV-positive Burkitt lymphoma from whole genome and transcriptome sequencing

2025-10-17

Abstract excerpt

<title>Abstract</title> <p>Epstein–Barr virus (EBV) is a ubiquitous human herpesvirus linked to multiple malignancies, but its role in disease remains uncertain. We analysed 410 EBV genomes, including 64 newly sequenced isolates from plasma of East African children with and without Burkitt lymphoma (BL), integrating whole-genome and transcriptomic data. Population genomic analyses revealed marked regional structu...

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Literature Corpus work
b12ae94a-a837-51ac-9581-f2f465bd3966
DOI
10.21203/rs.3.rs-7473738/v1
Open publication

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Evidence of latent-lytic replication in EBV-positive Burkitt lymphoma from whole genome and transcriptome sequencingDOI 10.21203/rs.3.rs-7473738/v1
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