Back to search

Article

Epstein Barr virus genomes reveal population structure and type 1 association with endemic Burkitt lymphoma

2019-07-02

Abstract excerpt

Endemic Burkitt lymphoma (eBL), the most prevalent pediatric cancer in sub-Saharan Africa, is associated with malaria and Epstein Barr virus (EBV). In order to better understand the role of EBV in eBL, we improved viral DNA enrichment methods and generated a total of 98 new EBV genomes from both eBL cases (N=58) and healthy controls (N=40) residing in the same geographic region in Kenya. Comparing cases and contro...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
891c4630-217e-5f2a-ab2f-b266cc5b0ea7
DOI
10.1101/689216
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Epstein Barr virus genomes reveal population structure and type 1 association with endemic Burkitt lymphomaDOI 10.1101/689216
Epstein-Barr Virus Genomes Reveal Population Structure and Type 1 Association with Endemic Burkitt Lymphoma.Semantic proximity
Evidence of latent-lytic replication in EBV-positive Burkitt lymphoma from whole genome and transcriptome sequencingSemantic proximity
Comprehensive Transcriptome and Mutational Profiling of Endemic Burkitt Lymphoma Reveals EBV Type-Specific Differences.Semantic proximity
Genome diversity of Epstein-Barr virus from multiple tumor types and normal infection.Semantic proximity
Expanding the Geographic Characterisation of Epstein–Barr Virus Variation through Gene-Based ApproachesSemantic proximity
Distinct Viral and Mutational Spectrum of Endemic Burkitt LymphomaSemantic proximity
Genetic Subgroups Inform on Pathobiology in Adult and Pediatric Burkitt LymphomaSemantic proximity
The impact of Epstein-Barr Virus genomic variations on clinical subtypes and prognosis in EBV-associated diseasesSemantic proximity
Epstein-Barr Virus Sequence Variation—Biology and DiseaseSemantic proximity
Comparative Genomic Analysis of Epstein‐Barr Virus Strains with a Focus on EBV2 VariabilitySemantic proximity
EBV Genome Variations and Association With Diseases.Semantic proximity
Reframing Burkitt lymphoma: virology not epidemiology defines clinical variantsSemantic proximity
Select a neighboring publication to make it the new centre.