Article

Succinylation participates in the progress of Idiopathic pulmonary fibrosis through mitochondrial energy metabolism

2024-01-25

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold> A new pathogenic role for mitochondrial dysfunction has been associated with aging and correlated with the development of idiopathic pulmonary fibrosis (IPF). The latest study found that the lysine succinylation (Ksucc) is involved in many energy metabolism pathways and affects the metabolic process in mitochondria, making this modification highly valuable for st...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: b11e1851-22af-50a9-bc20-7d5eb290883a
DOI: 10.21203/rs.3.rs-3878025/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Succinylation participates in the progress of Idiopathic pulmonary fibrosis through mitochondrial energy metabolismDOI 10.21203/rs.3.rs-3878025/v1Read

Protein post-translational modification by lysine succinylation: Biochemistry, biological implications, and therapeutic opportunitiesSemantic proximity Read

SIRT5-mediated desuccinylation prevents mitochondrial dysfunction in Alveolar epithelial cells senescence and Pulmonary fibrosisSemantic proximity Read

Dysregulation of protein succinylation and disease developmentSemantic proximity Read

Succinate dehydrogenase complex subunit C: Role in cellular physiology and disease.Semantic proximity Read

Succinylation and redox status in cancer cellsSemantic proximity Read

Gut flora-derived succinate exacerbates Allergic Airway Inflammation by promoting protein succinylationSemantic proximity Read

Proteomic Quantification of Lysine Acetylation and Succinylation Profile Alterations in Lung Adenocarcinomas of Non-Smoking FemalesSemantic proximity Read

Succinate Dehydrogenase Complex: An Updated ReviewSemantic proximity Read

Identification of Lysine Succinylation Substrates and the Succinylation Regulatory Enzyme CobB in Escherichia coliSemantic proximity Read

Systematic Analysis of Lysine Succinylation in Vero cells infected with Small Ruminant MorbillivirusSemantic proximity Read

Succinylation-related molecular activities in cancer: metabolic adaptations, immune landscape, and prognostic significance in colorectal cancerSemantic proximity Read

Serum Proteomics Identifies Biomarkers Associated With the Pathogenesis of Idiopathic Pulmonary FibrosisSemantic proximity Read