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Succinate Dehydrogenase Complex: An Updated Review

5 Oct 2018

Abstract excerpt

Succinate dehydrogenase (SDH) is uniquely tasked with a dual role in the essential energy-producing processes of a cell. Although SDH subunits and assembly factors form part of the same enzyme complex, mutations in their respective genes lead to significantly different clinical phenotypes. Remarkable discoveries in the last 17 years have led to the delineation of the SDH complex deficiency syndrome and its...

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PMID: 30289269
DOI: 10.5858/arpa.2017-0285-rs

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