Article

Nitrite Protects Against Cardiac Surgery-Associated Acute Kidney Injury via Inflammation Suppression: Insights from a Rat Cardiopulmonary Bypass Model

2025-10-16

Abstract excerpt

<title>Abstract</title> <p>Cardiac surgery-associated acute kidney injury (CS-AKI) occurs in 20–30% of patients undergoing cardiac surgery and is associated with poor prognosis and increased healthcare burden. Despite its clinical importance, effective preventive strategies remain lacking due to the complex and poorly understood mechanisms involved. Nitrite, a nitric oxide donor active under hypoxic conditions, h...

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Literature Corpus work: 21ac02f0-e13c-5e26-8bc1-06fe4bc1d968
DOI: 10.21203/rs.3.rs-6986859/v1

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