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Non-coding RNA therapeutics for cardiac regeneration

20 Mar 2020

Abstract excerpt

A growing body of evidence indicates that cardiac regeneration after myocardial infarction can be achieved by stimulating the endogenous capacity of cardiomyocytes (CMs) to replicate. This process is controlled, both positively and negatively, by a large set of non-coding RNAs (ncRNAs). Some of the microRNAs (miRNAs) that can stimulate CM proliferation is expressed in embryonic stem cells and is required to...

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PMID: 32215566
DOI: 10.1093/cvr/cvaa071

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