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Article

The Efficacy of the Interferon Alpha/Beta Response versus Arboviruses Is Temperature Dependent

23 Apr 2018

Abstract excerpt

ABSTRACT Interferon alpha/beta (IFN-α/β) is a critical mediator of protection against most viruses, with host survival frequently impossible in its absence. Many studies have investigated the pathways involved in the induction of IFN-α/β after virus infection and the resultant upregulation of antiviral IFN-stimulated genes (ISGs) through IFN-α/β receptor complex signaling. However, other than examining the...

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PMID: 29691338
DOI: 10.1128/mbio.00535-18

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