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Article

The evolving mpox threat (2022-2024): clade dynamics, immune evasion, and escalating global health challenges.

Frontiers in cellular and infection microbiology - 1 Jan 2025

Irfan Khan Muhammad, Saleh Ahmed A, Ali Rahmat, Jan Rifat Ullah, Gu Jie, Dejun Ji

Abstract excerpt

The 2022-2024 global Mpox outbreak, declared a Public Health Emergency of International Concern, marks a pivotal shift in the virus's epidemiology, extending beyond its traditional endemic regions in Africa. This review provides a comprehensive synthesis of the evolving Mpox threat, analyzing the dynamics of MPXV clades (I, Ia/Ib, II, IIa/IIb), with a focus on the enhanced transmissibility of the emergent Clade...

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Identifiers

PMID: 41737841
DOI: 10.3389/fcimb.2025.1677762
PMCID: PMC12926478

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