Article

Tracer-based metabolomics for profiling nitric oxide metabolites in a 3D microvessel-on-a-chip model

2023-12-04

Abstract excerpt

Endothelial dysfunction is a common denominator in cardiovascular diseases (CVDs) associated with diabetes, hypertension, obesity, renal failure or hypercholesterolemia. In these disease states, circulating adverse metabolic or hemostatic risk factors drive the progression of inflammation, thrombosis, platelet activation and atherosclerosis. A hallmark of endothelial dysfunction is the reduced bioavailability of n...

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Literature Corpus work: b075e299-1e3c-5a37-9272-50b6946aea8d
DOI: 10.1101/2023.12.03.569402

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