Article

Illuminating protein space with a programmable generative model

2022-12-02

Abstract excerpt

Three billion years of evolution have produced a tremendous diversity of protein molecules, and yet the full potential of this molecular class is likely far greater. Accessing this potential has been challenging for computation and experiments because the space of possible protein molecules is much larger than the space of those likely to host function. Here we introduce Chroma, a generative model for proteins and...

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Identifiers and source

Literature Corpus work: b05e1d80-7543-5a49-b1ce-6885cd979e38
DOI: 10.1101/2022.12.01.518682

Open publication

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