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Berberine Inhibits FoxM1 Dependent Transcriptional Regulation of POLE2 and Interferes with the Survival of Lung Adenocarcinoma

2021-09-14

Abstract excerpt

<title>Abstract</title> <p><bold>Background：</bold>Berberine is one of the most interesting and promising natural anticancer drugs. POLE2 is involved in many cellular functions such as DNA replication and is highly expressed in a variety of cancers. However, the specific molecular mechanism of berberine interfering with POLE2 expression in lung adenocarcinoma (LUAD) is still unknown to a great extent.<bold>Method...

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Literature Corpus work
b04eb672-7958-5d52-ad39-5c77ea2115a1
DOI
10.21203/rs.3.rs-845748/v1
Open publication

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Berberine Inhibits FoxM1 Dependent Transcriptional Regulation of POLE2 and Interferes with the Survival of Lung AdenocarcinomaDOI 10.21203/rs.3.rs-845748/v1
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