Article

TIGAR promotes malignant proliferation of NSCLC by modulating deoxynucleotide anabolism via a YBX1-RRM2B axis

2023-04-26

Abstract excerpt

<h4>Background: </h4> Lung cancer is one of the most common causes of cancer-related death worldwide due to its rapid growth and metastasis. TIGAR plays a role in promoting survival in various cancer cells, but the molecular mechanisms on metabolic reprogram in tumor cells are not fully understood. <h4>Methods: </h4>: TIGAR expression was detected in lung cancer by western blot and immunohistochemistry. A shRNA i...

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Literature Corpus work: 68a5497b-ff18-59a6-bf4d-98900a182bd2
DOI: 10.21203/rs.3.rs-2845674/v1

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