Article

NEBULA: a fast negative binomial mixed model for differential expression and co-expression analyses of large-scale multi-subject single-cell data

2020-09-25

Abstract excerpt

The growing availability of large-scale single-cell data revolutionizes our understanding of biological mechanisms at a finer resolution. In differential expression and co-expression analyses of multi-subject single-cell data, it is important to take into account both subject-level and cell-level overdispersions through negative binomial mixed models (NBMMs). However, the application of NBMMs to large-scale single...

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Literature Corpus work: b042acdb-e058-54d3-84e6-25dfb8d1c321
DOI: 10.1101/2020.09.24.311662

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