Article

The Interleukin-1 Receptor/Toll-Like Receptor Superfamily: Signal Transduction During Inflammation and Host Defense

2003-02-25

Abstract excerpt

The signal transduction pathways activated by the proinflammatory cytokine interleukin-1 (IL-1) have been the focus of much attention because of the important role that IL-1 plays in inflammatory diseases. A number of proteins have been described that participate in the post-receptor activation of the transcription factor nuclear factor κB (NF-κB), and stress-activated protein kinases such as p38 mitogen-activated...

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Literature Corpus work: b03d98db-d548-56fa-b9a5-14ecdb8d8854
DOI: 10.1126/scisignal.1712003re3

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