Article
TLR10: Insights, controversies and potential utility as a therapeutic target.
Scandinavian journal of immunology - 1 Apr 2021
Su Si-Biao, Tao Lin, Deng Ze-Ping, Chen Wen, Qin Shan-Yu, Jiang Hai-Xing
Abstract excerpt
The Toll-like receptor (TLR) family acts as a bridge connecting innate and acquired immunity. TLR10 remains one of the least understood members of this family. Some studies have examined TLR10 ligands, dimerization of TLR10 with other TLRs, and downstream signalling pathways and functions, but they have often arrived at conflicting conclusions. TLR10 can induce the production of proinflammatory cytokines by...
Topics
- Animals
- Autoimmune Diseases
- Cytokines
- Humans
- Inflammation
- Polymorphism, Single Nucleotide
- Signal Transduction
- Toll-Like Receptor 10
