Article

Catestatin improves heart metabolic flexibility by promoting mitochondrial structure and function

2024-12-30

Abstract excerpt

Hypertension, a major cause of cardiomyopathy, is one of the most critical risk factors for heart failure and mortality worldwide. Loss of metabolic flexibility of cardiomyocytes is one of the major causes of heart failure. Although Catestatin (CST) treatment is known to be both hypotensive and cardioprotective, its effect on cardiac metabolism is unknown. In this study, we undertook a transcriptomic approach to i...

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Literature Corpus work: b002fbef-ba87-5226-96a0-883843680409
DOI: 10.1101/2024.12.29.630689

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