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A systems‑level scoping review of multi‑omic markers in obesity‑ and type 2 diabetes‑associated diastolic dysfunction: An integrated three‑module framework

2026-06-09

Abstract excerpt

<title>Abstract</title> <p>Background Obesity and type 2 diabetes mellitus (T2DM) drive left ventricular diastolic dysfunction (LVDD) and heart failure with preserved ejection fraction (HFpEF), yet a systems-level model linking multi-omic markers to actionable therapeutic nodes is lacking. Methods We performed a scoping review of Web of Science, PubMed and ScienceDirect for studies published from inception unti...

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Literature Corpus work
93d51c10-2bd2-59de-9be5-476900079e59
DOI
10.21203/rs.3.rs-9950654/v1
Open publication

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A systems‑level scoping review of multi‑omic markers in obesity‑ and type 2 diabetes‑associated diastolic dysfunction: An integrated three‑module frameworkDOI 10.21203/rs.3.rs-9950654/v1
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