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Multi-omics insights into the pathogenesis of diabetic cardiomyopathy: epigenetic and metabolic profiles

2 Dec 2024

Abstract excerpt

AIM: Diabetic cardiomyopathy (DbCM), a complex metabolic disease, greatly threatens human health due to therapeutic limitations. Multi-omics approaches facilitate the elucidation of its intrinsic pathological changes. METHODS: Metabolomics, RNA-seq, proteomics, and assay of transposase-accessible chromatin (ATAC-seq) were utilized to elucidate multidimensional molecular alterations in DbCM. RESULTS: In the heart...

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Cardiovascular Function and Risk Factors
Kruppel-like factors research
Peroxisome Proliferator-Activated Receptors

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39623870
DOI: 10.1080/17501911.2024.2435257

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