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From Transcriptomic Signatures to Active-Site Docking and ADMET Properties Prediction: Bioinformatics-Guided Exploration of Binding Mechanisms of Cardioprotective Phytoconstituents Against Dysregulated Targets in Hypertrophic Cardiomyopathy

2024-10-15

Abstract excerpt

Hypertrophic cardiomyopathy (HCM) is a global health problem characterized by left ventricle become thick and stiff with effect of indication including chest pain, fluttering, fainting and shortness of breath. In this investigation, we aimed to identify diagnostic markers and analyzed the therapeutic potential of essential genes. Next generation sequencing (NGS) dataset GSE180313 was obtained from the Gene Express...

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Literature Corpus work
d4dd0633-c501-5311-9096-8f4d410e172b
DOI
10.1101/2024.10.13.618070
Open publication

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From Transcriptomic Signatures to Active-Site Docking and ADMET Properties Prediction: Bioinformatics-Guided Exploration of Binding Mechanisms of Cardioprotective Phytoconstituents Against Dysregulated Targets in Hypertrophic CardiomyopathyDOI 10.1101/2024.10.13.618070
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