Article

Functional transcriptomic landscape informs novel therapeutic strategies in multiple myeloma

2022-07-06

Abstract excerpt

<title>Abstract</title> <p>We present a unique database of tumor samples from 399 multiple myeloma (MM) patients, whose functional genomic landscape was assessed by integrating ex vivo drug sensitivity to 138 drugs, clinical variables, cytogenetics, mutational profiles and transcriptomes. These analyses revealed a novel MM transcriptomic topology that, when associated with ex vivo drug sensitivity, generates “foo...

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Literature Corpus work: afdf0bd0-14be-5dd8-ba2e-26d8bac4f450
DOI: 10.21203/rs.3.rs-1723993/v1

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