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Integrative multi-omics identifies high risk Multiple Myeloma subgroup associated with significant DNA loss and dysregulated DNA repair and cell cycle pathways

2021-09-29

Abstract excerpt

<h4>Background: </h4> Despite significant therapeutic advances in improving lives of Multiple Myeloma (MM) patients, it remains mostly incurable, with patients ultimately becoming refractory to therapies. MM is a genetically heterogeneous disease and therapeutic resistance is driven by a complex interplay of disease pathobiology and mechanisms of drug resistance. We applied a multi-omics strategy using tumor-deriv...

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Literature Corpus work
0ef5459f-6095-5905-94c7-c1b61c09a5ee
DOI
10.21203/rs.3.rs-923792/v1
Open publication

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Integrative multi-omics identifies high risk Multiple Myeloma subgroup associated with significant DNA loss and dysregulated DNA repair and cell cycle pathwaysDOI 10.21203/rs.3.rs-923792/v1
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