Article

Gut microbiota mediates trafficking of intestinal T cells to the brain to exacerbate neuroinflammation after ischemic stroke

2025-06-29

Abstract excerpt

<title>Abstract</title> <p>Ischemic stroke disrupts neuroimmune homeostasis, leading to pronounced neurological impairment, yet the cellular mechanisms remain incompletely defined. Here, we construct a high-resolution spatiotemporal immune atlas of infarcted brain regions from post-stroke patients using imaging mass cytometry, revealing a marked perivascular accumulation of PD-1⁺ T cells. Parallel investigations...

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Literature Corpus work: afc6e88d-33ac-58ee-bfd7-2f5880331a4b
DOI: 10.21203/rs.3.rs-6952560/v1

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