Article

The SARS-CoV-2 Transcriptional Metabolic Signature in Lung Epithelium

2020-07-14

Abstract excerpt

Viruses are efficient metabolic engineers that actively rewire host metabolic pathways to support their lifecycle. Charting SARS-CoV-2 induced metabolic changes in lung cells could offer insight into COVID-19 pathogenesis while presenting new therapeutic targets. Here we show that the transcriptional response SARS-CoV-2 in primary lung epithelial cells and biopsies of COVID-19 patients is predominantly metabolic....

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Identifiers and source

Literature Corpus work: af892e32-7662-510f-b110-9a5133180715
DOI: 10.2139/ssrn.3650499

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