Article

Interferon Regulatory Factor 5 (IRF5) Interacts with the Translation Initiation Complex and Promotes mRNA Translation During the Integrated Stress Response to Amino Acid Deprivation

2017-07-15

Abstract excerpt

<h4>ABSTRACT</h4> Interferon Regulatory Factor 5 (IRF5) plays an important role in limiting pathogenic infection and tumor development. Host protection by IRF5 can occur through a variety of mechanisms including production of type I interferon and cytokines as well as the regulation of cell survival, growth, proliferation, and differentiation. While modulation of these cellular processes is attributed to IRF5 tra...

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Literature Corpus work: af7793c3-e9f7-54f0-b0cd-debf0eb545d0
DOI: 10.1101/163998

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