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Article

Cellular IRES-mediated translation

14 Jan 2011

Abstract excerpt

Translation of cellular mRNAs via initiation at Internal Ribosome Entry Sites (IRESs) has received increased attention during recent years due to its emerging significance for many physiological and pathological stress conditions in eukaryotic cells. Expression of genes bearing IRES elements in their mRNAs is controlled by multiple molecular mechanisms, with IRES-mediated translation favored under conditions when...

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PMID: 21220943
DOI: 10.4161/cc.10.2.14472

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