Article
A Novel Therapeutic Target, BACH1, Regulates Cancer Metabolism
2021-01-29
Abstract excerpt
BTB domain and CNC homology 1 (BACH1) is a highly expressed transcription factor in tumors including breast and lung, relative to their non-tumor tissues. BACH1 is known to regulate multiple physiological processes including heme homeostasis, oxidative stress response, senescence, cell cycle, and mitosis. In a tumor, BACH1 promotes invasion and metastasis of cancer cells, and the expression of BACH1 presents a poo...
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Identifiers and source
- Literature Corpus work
- af5771a2-6243-560e-a249-6a9c4afa7849
- DOI
- 10.20944/preprints202101.0626.v1
