Article
Altered gene expression in glycolysis-cholesterol synthesis axis correlates with outcome of triple-negative breast cancer.
Experimental biology and medicine (Maywood, N.J.) - 1 Mar 2021
Zhong Peng-Cheng, Shu Rong, Wu Hui-Wen, Liu Zhi-Wen, Shen Xiao-Ling, Hu Ying-Jie
Abstract excerpt
Identification of molecular subtypes of clinically resectable triple-negative breast cancer (TNBC) is of great importance to achieve better clinical outcomes. Inter- and intratumor metabolic heterogeneity improves cancer survival, and the interaction of various metabolic pathways may affect treatment outcome of TNBC. We speculated that TNBC can be categorized into prognostic metabolic subtype according to the...
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