Article

Loss of Neuroligin 4X Induces An Intrinsic Innate Immune Response in TNBC

2021-07-13

Abstract excerpt

<title>Abstract</title> <p><bold>Background </bold>Immune checkpoint blockade therapies, which act on T cell inhibitory receptors, including CTLA-4 and PD-1, induce durable responses across diverse cancers. However, most patients do not respond to these therapies, and initially responsive cancers may relapse. Identifying molecular mechanisms that influence therapeutic responses and resistance is critical to reali...

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Literature Corpus work: af40adbf-0009-581c-a579-58782fb72c8a
DOI: 10.21203/rs.3.rs-565425/v2

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