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Article

Homeoprotein neuroprotection of embryonic neuronal cells

2019-07-08

Abstract excerpt

<h4>ABSTRACT</h4> Most homeoprotein transcription factors have a highly conserved internalization domain used in intercellular transfer. Internalization of homeoproteins ENGRAILED1 or ENGRAILED2 promotes the survival of adult dopaminergic cells, whereas that of OTX2 protects adult retinal ganglion cells. Here we characterize the in vitro neuroprotective activity of several homeoproteins in response to H 2 O 2...

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Literature Corpus work
af1c679b-0b28-547b-8f4b-060b46a94cdd
DOI
10.1101/695684
Open publication

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