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Article

Mammalian numb-interacting protein 1/dual oxidase maturation factor 1 directs neuronal fate in stem cells.

The Journal of biological chemistry - 4 Jun 2010

Kennedy Karen A M, Ostrakhovitch Elena A, Sandiford Shelley D E, Dayarathna Thamara, Xie Xiaojun, Waese Elaine Y L, Chang Wing Y, Feng Qingping, Skerjanc Ilona S, Stanford William L, Li Shawn S C

Abstract excerpt

In this study, we describe a role for the mammalian Numb-interacting protein 1 (Nip1) in regulation of neuronal differentiation in stem cells. The expression of Nip1 was detected in the developing mouse brain, embryonic stem cells, primary neuronal stem cells, and retinoic acid-treated P19 embryonal carcinoma cells. The highest expression of Nip1 was observed in undifferentiated neuronal stem cells and was...

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Identifiers

PMID: 20233719
DOI: 10.1074/jbc.M109.084616
PMCID: PMC2878559

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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