Article

nanoBERT: A deep learning model for gene agnostic navigation of the nanobody mutational space

2024-02-02

Abstract excerpt

Nanobodies are a subclass of immunoglobulins, whose binding site consists of only one peptide chain, bestowing favorable biophysical properties. Recently, the first nanobody therapy was approved, paving the way for further clinical applications of this antibody format. Further development of nanobody-based therapeutics could be streamlined by computational methods. One of such methods is infilling - positional pre...

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Literature Corpus work: aeeff200-30c8-572a-865c-6af358177d30
DOI: 10.1101/2024.01.31.578143

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