Article

Structural Brain Age Trajectories in Antipsychotic-naive First Episode Psychosis

2026-06-02

Abstract excerpt

<h4>Background</h4> Psychotic disorders such as schizophrenia have been associated with older-appearing brain structure, commonly quantified using the brain-age paradigm. However, it remains unclear whether these alterations are present at illness onset and whether antipsychotic treatment modifies their trajectory. <h4>Methods</h4> In this study, 61 (28 females and 33 males) antipsychotic-naïve people with first...

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Literature Corpus work: aeca40de-051e-5323-8adc-5bcc670e9308
DOI: 10.64898/2026.05.25.26353865

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