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Meta-analyses of epigenetic age acceleration and GrimAge components of schizophrenia or first-episode psychosis

15 Nov 2024

Abstract excerpt

Schizophrenia is a common chronic psychiatric disorder that causes age-related dysfunction. The life expectancy in patients with schizophrenia is ≥10 years shorter than that in the general population because of the higher risk of other diseases, such as cardiovascular diseases. Aging studies based on DNA methylation status have received considerable attention. Several epigenetic age accelerations and predicted...

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PMID: 39548083
DOI: 10.1038/s41537-024-00531-8

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