Probing the Biological Underpinnings of Advanced Brain Ageing in Schizophrenia

Abstract excerpt

<h4>Background</h4> Recent evidence suggests that patients with schizophrenia may show advanced brain ageing, particularly evident after the first year of onset. However, it is unclear if accelerated ageing relents, persists or continues to increase over time. The underlying causal factors are also poorly understood. Disruptions in glutamate function, oxidative stress, and inflammation may all contribute to progre...

Topics

Open a Topic to create a Post that cites this publication.

• Advanced Neuroimaging Techniques and Applications
• Birth, Development, and Health
• Diet and metabolism studies
• Epigenetics and DNA Methylation
• Functional Brain Connectivity Studies
• Neuroinflammation and Neurodegeneration Mechanisms
• Schizophrenia research and treatment
• Tryptophan and brain disorders

Identifiers and source

Literature Corpus work

02eeba3c-3795-544a-b08c-dd0bda399bf5

DOI

10.1101/2024.07.05.24309965