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Accelerated aging in the brain, epigenetic aging in blood, and polygenic risk for schizophrenia

18 Apr 2021

Abstract excerpt

Schizophrenia patients show signs of accelerated aging in cognitive and physiological domains. Both schizophrenia and accelerated aging, as measured by MRI brain images and epigenetic clocks, are correlated with increased mortality. However, the association between these aging measures have not yet been studied in schizophrenia patients. In schizophrenia patients and healthy subjects, accelerated aging was...

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PMID: 33882370
DOI: 10.1016/j.schres.2021.04.005

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