Article
Functional Role of RRS1 in the Chemosensitivity of Drug Resistant Breast Cancer Cell to Cisplatin
2021-10-29
Abstract excerpt
RRS1(human regulator of ribosome synthesis 1), a critical nuclear protein participated in ribosome biogenesis, plays important roles in the genesis and development of breast cancer. Here, we reported that RRS1 was highly expressed in cisplatin resistant breast cancer cell MCF-7/DDP than that in parent MCF-7. RRS1 silencing increased the sensitivity of MCF-7/DDP cells to cisplatin, inhibited proliferation, affected...
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Identifiers and source
- Literature Corpus work
- aebd4c37-b0d1-560c-afe2-0d3f5c0a1bbd
- DOI
- 10.21203/rs.3.rs-1016726/v1
