Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Down Regulation of CIAPIN1 Reverses Multidrug Resistance in Human Breast Cancer Cells by Inhibiting MDR1

20 Jun 2012

Abstract excerpt

Cytokine-induced apoptosis inhibitor 1 (CIAPIN1), initially named anamorsin, a newly indentified antiapoptotic molecule is a downstream effector of the receptor tyrosine kinase-Ras signaling pathway. Current study has revealed that CIAPIN1 may have wide and important functions, especially due to its close correlations with malignant tumors. However whether or not it is involved in the multi-drug resistance (MDR)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Drug Transport and Resistance Mechanisms
Share to Nanoparticle-Based Drug Delivery
Share to RNA Interference and Gene Delivery

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22717413
DOI: 10.3390/molecules17067595

Provenance

PubMed metadata and Literature Corpus relationships.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Down Regulation of CIAPIN1 Reverses Multidrug Resistance in Human Breast Cancer Cells by Inhibiting MDR1PMID 22717413Read ↗

IAP family protein expression correlates with poor outcome of multiple myeloma patients in association with chemotherapy-induced overexpression of multidrug resistance genesSemantic proximity Read ↗

Targeting the inhibitors of apoptosis proteins (IAPs) to combat drug resistance in cancersSemantic proximity Read ↗

Functional Role of RRS1 in the Chemosensitivity of Drug Resistant Breast Cancer Cell to CisplatinSemantic proximity Read ↗

XIAP’s Profile in Human CancerSemantic proximity Read ↗

Birinapant Enhances Gemcitabine's Antitumor Efficacy in Triple-Negative Breast Cancer by Inducing Intrinsic Pathway–Dependent ApoptosisSemantic proximity Read ↗

The Effects of Chemotherapeutic Drugs on PD-L1 Gene Expression in Breast Cancer Cell LinesSemantic proximity Read ↗

Recent advances in understanding inhibitor of apoptosis proteinsSemantic proximity Read ↗

miR-200bc/429 cluster modulates multidrug resistance of human cancer cell lines by targeting BCL2 and XIAPSemantic proximity Read ↗

Identification of a new class of natural product MDM2 inhibitor:In vitroandin vivoanti-breast cancer activities and target validationSemantic proximity Read ↗

Integrin β4 promotes DNA damage-related drug resistance in triple-negative breast cancer via TNFAIP2/IQGAP1/RAC1Semantic proximity Read ↗

Integrin β4 promotes DNA damage-related drug resistance in triple-negative breast cancer via TNFAIP2/IQGAP1/RAC1Semantic proximity Read ↗

Expression patterns of cell cycle and apoptosis‐related genes in a multidrug‐resistant human colon carcinoma cell lineSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.