Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Targeting the chromatin remodeling enzyme BRG1 increases the efficacy of chemotherapy drugs in breast cancer cells

25 Mar 2016

Abstract excerpt

// Qiong Wu 1 , Soni Sharma 2 , Hang Cui 1,3 , Scott E. LeBlanc 1 , Hong Zhang 1 , Rohini Muthuswami 2 , Jeffrey A. Nickerson 1 and Anthony N. Imbalzano 1 1 Department of Cell and Developmental Biology, University of Massachusetts Medical School, Worcester, MA, USA 2 School of Life Sciences, Jawaharlal Nehru University, New Delhi, Delhi, India 3 Abace Biotech Co Ltd., Yi Zhuang Biomedical Park, BDA, Beijing,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Mechanisms and Therapy
Share to Chromatin Remodeling and Cancer
Share to Mechanisms of cancer metastasis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27029062
DOI: 10.18632/oncotarget.8384

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Targeting the chromatin remodeling enzyme BRG1 increases the efficacy of chemotherapy drugs in breast cancer cellsPMID 27029062Read ↗

BRG1 targeting overcomes ABCC-based multidrug resistance induced by paclitaxelSemantic proximity Read ↗

BRG1 Is a Prognostic Marker and Potential Therapeutic Target in Human Breast CancerSemantic proximity Read ↗

The BRG1 ATPase of Human SWI/SNF Chromatin Remodeling Enzymes as a Driver of CancerSemantic proximity Read ↗

The reversible epigenetic silencing of BRM: implications for clinical targeted therapy.Semantic proximity Read ↗

The Activity of p53 Is Differentially Regulated by Brm- and Brg1-containing SWI/SNF Chromatin Remodeling ComplexesSemantic proximity Read ↗

BRG1, the ATPase subunit of SWI/SNF chromatin remodeling complex, interacts with HDAC2 to modulate telomerase expression in human cancer cellsSemantic proximity Read ↗

BET inhibitors as novel therapeutic agents in breast cancerSemantic proximity Read ↗

Pharmacologic reversal of epigenetic silencing of the anticancer protein BRM: a novel targeted treatment strategySemantic proximity Read ↗

Brahma-Related Gene-1 (BRG1) promotes the malignant phenotype of glioblastoma cells.Semantic proximity Read ↗

Promoter methylation patterns of ABCB1, ABCC1 and ABCG2 in human cancer cell lines, multidrug-resistant cell models and tumor, tumor-adjacent and tumor-distant tissues from breast cancer patientsSemantic proximity Read ↗

ABC transporters in breast cancer: their roles in multidrug resistance and beyondSemantic proximity Read ↗

Essential gene screening identifies the bromodomain-containing protein BRPF1 as a new actionable target for endocrine therapy-resistant breast cancersSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.