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T Lymphocyte-Macrophage Hybrid Membrane-Coated Biomimetic Nanoparticles Alleviate Myocarditis via Suppressing Pyroptosis by Targeting Gene Silencing

2024-04-09

Abstract excerpt

Utilizing small interfering RNA (siRNA) for gene silencing presents a viable strategy for treating human diseases, including cardiovascular disorders. However, the strategic targeting and delivery of siRNA therapeutics to desired tissues or cell subtypes, followed by endosomal escape into the cytosol, remain challenging. Based on previous research, we identified interferon regulatory factor 1 (IRF1)-mediated macro...

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Literature Corpus work
aeb05a83-889a-528d-aee0-daa49ab22fe1
DOI
10.21203/rs.3.rs-4206914/v1
Open publication

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T Lymphocyte-Macrophage Hybrid Membrane-Coated Biomimetic Nanoparticles Alleviate Myocarditis via Suppressing Pyroptosis by Targeting Gene SilencingDOI 10.21203/rs.3.rs-4206914/v1
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